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Three vs 12-month DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary stent: a randomised clinical trial
1. 3 months of dual antiplatelet therapy (DAPT) in patients treated with Firehawk stents was non-inferior to 12 months of DAPT for the primary composite event of all-cause death, myocardial...
Association between atrial fibrillation and both the in-hospital mortality and disease severity in acute pancreatitis: insights from a multicenter study
1. Among patients with acute pancreatitis (AP), a history of atrial fibrillation (AF) was associated with increased disease severity but not in-hospital mortality. Evidence Rating Level: 2 (Good) AP is...
Effect of adjuvant carboplatin intensified chemotherapy versus standard chemotherapy on survival in women with high risk, early stage, triple negative breast cancer (CITRINE): randomised, open label phase 3 trial
1. Among patients with high-risk, early-stage triple-negative breast cancer, the addition of carboplatin to a standard anthracycline/taxane adjuvant chemotherapy regimen significantly improved survival outcomes with a reduction in early recurrence...
Machine learning models effectively screened for Parkinson’s disease using smile videos
1. Adnan and colleagues evaluated machine learning models’ ability to screen for Parkinson’s disease using self-recorded smile videos. 2. The models achieved high sensitivity and specificity among patient cohorts from...
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Explore the Classics Series™
![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](data:image/svg+xml;nitro-empty-id=ODY4OjE0MTY=-1;base64,PHN2ZyB2aWV3Qm94PSIwIDAgMSAxIiB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==)
EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
Ablation may reduce stroke risk, death, heart failure hospitalization in patients with atrial fibrillation
1. In this systematic review and meta-analysis, catheter ablation was found to reduce overall risk of ischemic stroke, hospitalization...
Breast cancer survivors may have a lower risk of Alzheimer’s dementia
1. In this retrospective cohort study, breast cancer survivors had a lower risk of Alzheimer’s dementia compared with cancer-free...
Repeated medial branch blocks do not improve pain outcomes for thermal radiofrequency ablation
1. For patients with facet-mediated spine pain that achieve ≥80% pain relief after a medial branch block, a second...
