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Factors in the Initial Resuscitation of Patients With Severe Trauma: The FiiRST-2 Randomized Clinical Trial

October 3, 2025

Risk of autism in offspring linked to maternal pregestational diabetes and severe obesity

Antioxidant Treatment and the Chance to Conceive in Men Seeking Fertility Care: The SUMMER Randomized Clinical Trial

October 3, 2025

1. In a cohort of men trying to conceive, the use of antioxidants did not significantly improve pregnancy rates compared to a placebo. 2. In the “optimal treatment window,” pregnancy...

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults

DAWN Trial: Redefining the Treatment Window for Stroke Thrombectomy

byDeepti Shroff Karhade

October 3, 2025

Why DAWN Changed Stroke Care The DAWN trial (DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late-Presenting Strokes Undergoing Neurointervention with Trevo) redefined the timeline...

Children’s hospital visits for suicide ideation and attempts are increasing

Efficacy and Safety of Ammoxetine in Major Depressive Disorder

byAlex Xiangand1 others

October 2, 2025

1. Ammoxetine, a novel SNRI developed from duloxetine, was effective at treating adults with major depressive disorder (MDD) and was safe and well-tolerated. Evidence Rating Level: 1 (Excellent) The World...

A collection of symbolic items such as a microscope

CASPer Exam: Transforming Medical School Admissions

byDeepti Shroff Karhade

October 2, 2025

Why CASPer Matters The CASPer exam (Computer-Based Assessment for Sampling Personal Characteristics) has become an increasingly common requirement in medical school admissions. Unlike grade point average (GPA) or the Medical...

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Explore the Classics Series™

ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]

EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]

byMarc Succi

August 27, 2025

1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...