Universal Health Services acquisition of Talkspace connects virtual and inpatient behavioral care
1. Universal Health Services (UHS's) $835 million acquisition of Talkspace combines a national virtual behavioral health platform with a large network of outpatient, crisis, acute, and inpatient psychiatric services, creating...
Cataract surgery is associated with increased incidence of diabetic retinopathy among patients with diabetes
1. Cataract surgery in patients with diabetes is associated with a significantly increased incidence of diabetic retinopathy (DR). Evidence Rating Level: 2 (Good) DR is a significant cause of blindness...
Molecularly guided therapy may improve outcomes in patients with unfavourable cancer of unknown primary compared with standard chemotherapy
1. The use of molecularly guided therapy (MGT) was associated with significantly improved progression-free survival (PFS) compared with standard platinum-based chemotherapy in patients with unfavourable cancer of unknown primary (CUP). ...
Methadone initiation linked to lower mortality compared to buprenorphine-naloxone after opioid overdose
1. In this retrospective cohort study examining people who had survived a recent opioid overdose, initiating methadone was associated with lower all-cause mortality over the following year compared with initiating...
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Explore the Classics Series™
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EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated clinical tool that estimates the short-term risk of stroke following a transient...
Child-Pugh Score: Prognosis, Classification & Cirrhosis Staging in Chronic Liver Disease [Classics Series]
1. The Child-Pugh score, derived from five clinical and lab measures (bilirubin, albumin, INR/prothrombin time, ascites, encephalopathy), is widely...
POISE Trial: Perioperative Metoprolol Reduces MI but Increases Stroke & Mortality [Classics Series]
1. In adults undergoing noncardiac surgery, perioperative β-blocker therapy with extended-release metoprolol significantly reduced nonfatal myocardial infarction (MI) risk...
