Brelovitug met the AZURE-4 primary endpoint in chronic hepatitis delta infection in topline phase 3 results
Brelovitug met the AZURE-4 primary endpoint, with 59% achieving combined virologic response and ALT normalization at Week 24 versus 0% with delayed treatment.
Sexual minority health care providers report more depression, psychological distress, and cost-related barriers to care
1. In this cross-sectional study, health care providers (HCPs) identifying as a sexual minority reported more lifetime depression diagnoses and psychological distress. 2. Sexual minority HCPs were also more likely...
FDA Approves First DNA Medicine to Reduce Repeat Airway Surgeries
1. The FDA granted Voceryq accelerated approval for the treatment of recurrent respiratory papillomatosis. 2. Among patients using Voceryq in a clinical study, 27% required no surgeries in the first...
First-trimester doxycycline exposure may be linked to higher risk of pregnancy loss
1. In this retrospective cohort study, first-trimester exposure to doxycycline, as opposed to amoxicillin or macrolides, was associated with a greater risk for pregnancy loss in pregnant patients with respiratory...
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EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
BI-RADS study identifies mammography features with high positive predictive values for carcinoma [Classics Series]
1. Lesions observed in mammography with spiculated margins, linear calcification morphology, irregular shape, segmental calcification distribution, or linear calcification...
Thrombectomy between 6 and 24 hours after acute stroke reduces disability: The DAWN trial [Classics Series]
1. Thrombectomy performed between 6 and 24 hours after onset of acute stroke in patients with a mismatch between...
Ottawa ankle rules reduce the rate of referral for ankle radiography [Classics Series]
1. The Ottawa ankle rules significantly reduced referral for ankle, but not foot, radiography in the emergency department. 2....
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