1. In this interim analysis from a randomized controlled trial, adults with biopsy-proven IgA nephropathy and persistent proteinuria who received telitacicept had improved proteinuria compared to placebo. 2. Telitacicept was...
1. Exposure to systemic glucocorticoid immunosuppression (gsISP) close to immune checkpoint inhibitor (ICI) initiation was associated with worse overall survival (OS). Evidence Rating Level: 2 (Good) The introduction of ICIs...
1. In this randomized controlled trial, tirzepatide produced substantially greater reductions in HbA1c, body weight, waist circumference, and BMI than intensified conventional care (ICC) in adults with early type 2...
Validation of 2 Syncope Risk Scores and Comparison With Physician Risk Estimation 1. The Canadian Syncope Risk Score (CSRS) and FAINT score are effective at identifying which adult patients presenting...
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1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
1. In this systematic review and meta-analysis, catheter ablation was found to reduce overall risk of ischemic stroke, hospitalization...
1. In this retrospective cohort study, breast cancer survivors had a lower risk of Alzheimer’s dementia compared with cancer-free...
1. For patients with facet-mediated spine pain that achieve ≥80% pain relief after a medial branch block, a second...
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