The Scan by 2 Minute Medicine®: Viral menopause cocktail spreads without clinical evidence, maxxing trends raise body dysmorphia concerns, post-treatment opioid overdose risk remains high, Bundibugyo Ebola outbreak surpasses 5,000 cases, and coffee intake is linked to lower visceral fat
The Scan by 2 Minute Medicine® is a pop-culture medical newsletter and exclusive benefit for 2 Minute Medicine Plus subscribers. Viral menopause cocktail lacks evidence for treating vasomotor symptoms A...
Mortality in the post-housing period is high among homeless people in Ottawa, Canada
1. Among chronically homeless people who moved into supported housing units in Ottawa, Canada, the mortality rate was high at 22%. Evidence Rating Level: 2 (Good) Homeless people have markedly...
Higher parental vitamin B12 associated with fewer birth defects
1. In this prospective cohort study, higher parental preconception and maternal postconception vitamin B12 levels were associated with lower odds and prevalence of birth defects. 2. Higher folate levels were...
Newer GLP-1 agents yield substantial weight loss in nondiabetic adults
1. In this updated systematic review, glucagon-like peptide-1 receptor agonists and co-agonists produced substantial weight loss in adults without diabetes, with greater reductions observed with newer agents. 2. Newer agents...
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EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated clinical tool that estimates the short-term risk of stroke following a transient...
Child-Pugh Score: Prognosis, Classification & Cirrhosis Staging in Chronic Liver Disease [Classics Series]
1. The Child-Pugh score, derived from five clinical and lab measures (bilirubin, albumin, INR/prothrombin time, ascites, encephalopathy), is widely...
POISE Trial: Perioperative Metoprolol Reduces MI but Increases Stroke & Mortality [Classics Series]
1. In adults undergoing noncardiac surgery, perioperative β-blocker therapy with extended-release metoprolol significantly reduced nonfatal myocardial infarction (MI) risk...
