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Seven days of antibiotic treatment non-inferior to 14 days for bloodstream infections
1. In this randomized controlled trial, among hospitalized patients with a bloodstream infection, seven days of antibiotic treatment was found...
Remibrutinib alleviates symptoms in chronic spontaneous urticaria resistant to H1-antihistamines
1. In this randomized controlled trial, among patients with chronic spontaneous urticaria who continue to have symptoms while on second-generation...
Recognition of kidney allograft microvascular inflammation refines risk stratification for allograft outcomes
1. Patients with a nonrejection-related diagnosis according to the 2019 Banff classification who were reclassified as MVI, DSA-negative, and C4d-negative...
Intraosseous and intravenous vascular access are equally effective for ROSC following out-of-hospital cardiac arrest
1. In this randomized clinical trial, among patients who had an out-of-hospital cardiac arrest, no significant difference was found in...
Mpox cases in Africa continued to increase following WHO emergency declarations
1. The number of mpox cases in Africa increased leading up to the first mpox declaration of a Public Health...
Plozasiran reduces triglyceride levels and acute pancreatitis incidence in persistent chylomicronemia
1. In this randomized controlled trial, among patients with persistent chylomicronemia, it was found that plozasiran more effectively reduced fasting...
Levofloxacin does not prevent infection in children exposed to MDR tuberculosis
1. In this randomized controlled trial, among children and adolescents with household exposure to an adult with multidrug-resistant tuberculosis, it...
Nexiguran ziclumeran reduces serum TTR levels in transthyretin amyloid cardiomyopathy
1. In this phase one clinical trial, among patients with transthyretin amyloid cardiomyopathy (ATTR-CM), it was found that nexiguran ziclumeran...
Late-arresting attenuated parasite provides greater malaria protection than early-arresting parasite
1. In this randomized controlled trial, it was found that GA2, a late-arresting, genetically attenuated Plasmodium falciparum parasite, induced greater...
Collagenase injection is not noninferior to fasciectomy for Dupuytren’s contracture treatment
1. In this randomized controlled trial, among patients with moderate Dupuytren’s contracture, collagenase injection was not found to be noninferior...