Liberal transfusion strategy not beneficial in treating aneurysmal subarachnoid hemorrhage
1. Among critically ill adults with acute aneurysmal subarachnoid hemorrhage (SAH) and anemia, a liberal transfusion strategy did not improve...
AAV9.LAMP2B gene therapy shows clinical benefit in Danon disease
1. In seven patients with Danon disease, a single infusion of adeno-associated virus serotype 9 carrying transgene LAMP2B (AVV9.LAMP2B) therapy...
Emerging highly pathogenic avian influenza A(H5N1) infections in humans
1. In this case series, of the reported 46 case-patients, 45 cases were due to exposures to infected poultry or...
Perioperative chemotherapy improves survival in esophageal cancer
1. Among patients with resectable esophageal cancer, perioperative chemotherapy with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) resulted in improved survival...
Talquetamab and teclistamab combination improved response in relapsed multiple myeloma
1. In this randomized controlled trial, in patients with relapsed or refractory multiple myeloma (MM), combination therapy of talquetamab and...
Asundexian inferior to apixaban as anticoagulation therapy for atrial fibrillation
1. In this randomized controlled trial, among patients with atrial fibrillation requiring anticoagulation therapy, asundexian resulted in a high risk...
rVSV-ZEBOV-GP ring vaccination reduces the incidence of Ebola virus disease
1. In the outbreak of Ebola virus disease (EVD) in the Democratic Republic of Congo (DRC) between 2018 and 2020,...
Colchicine not beneficial after acute myocardial infarction for reducing cardiovascular events
1. In this randomized controlled trial, in patients who had a myocardial infarction, a three-year treatment with colchicine was not...
PCI beneficial in patients undergoing transcatheter aortic-valve implantation
1. In patients undergoing transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) with stable coronary artery disease (CAD),...
Addition of pembrolizumab to chemotherapy improves early-stage triple-negative breast cancer survival
1. In this randomized controlled trial, among patients with early-stage triple-negative breast cancer (TNBC), the addition of neoadjuvant and adjuvant...