![Engineered stem cells mitigate liver damage caused by radiation [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2014/12/Human_embryonic_stem_cells-350x250.png)
Human neural stem cell grafts in rhesus monkeys improve motor function after spinal cord injury [PreClinical]
1. Following cervical spinal cord injury, rhesus monkeys were grafted with human neural progenitor cells. 2. Over the course of...
Early diagnosis of HIV infection through analysis of oral fluid [Pre-Clinical]
1. A novel method – Antibody Detection by Agglutination-PCR (ADAP) – was developed to diagnose HIV in oral fluid samples....
Improved islet encapsulation device for the treatment of type 1 diabetes [PreClinical]
1. A device for islet transplantation for type 1 diabetes was designed and demonstrated to be safe and retrievable in...
![PET scans in early-stage Hodgkin’s lymphoma may help guide therapy [RAPID trial]](https://www.2minutemedicine.com/wp-content/uploads/2015/04/1280px-Hodgkin_lymphoma_cytology_large-350x250.jpg)
Novel β-chain-targeting approach for the treatment of lymphoma [PreClinical]
1. The β-chain constant region of the T cell receptor (TCR) was targeted to specifically eliminate a population of malignant...
Thyroid hormone supplementation may be a promising treatment for idiopathic pulmonary fibrosis [PreClinical]
1. An enzyme involved in thyroid hormone activation was found to be elevated in patients with pulmonary fibrosis. 2. Following...
Growth hormone releasing hormone (GHRH) agonists protects against diabetic retinopathy in animal model
1. GHRH and GHRH receptor levels are decreased in diabetic rats and humans. 2. Administration of GHRH agonists to diabetic...
Prenatal administration of novel compound treats Down syndrome in mice [PreClinical]
1. A chemical library screen identified a compound (termed altered generation of neurons, or ALGERNON) that promoted the proliferation of...
Targeting senescent cells prevents age-related bone loss in mice [PreClinical]
1. When three therapies that eliminate senescent cells were separately tested on aged mice, the animals demonstrated improved bone microarchitecture...
![Tumor-specific mutant antigens are potential targets for cancer therapy [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2014/12/mouse-e1417555547919-350x250.jpg)
Adiponectin treats some symptoms of polycystic ovarian syndrome in mice [PreClinical]
1. In mouse models of polycystic ovarian syndrome (PCOS), elevated adiponectin levels ameliorated metabolic dysfunction. 2. However, adiponectin was unable...
CRISPR-Cas9 corrects hypertrophic cardiomyopathy gene mutation in human preimplantation embryos [PreClinical]
1. The gene editing tool CRISPR-Cas9 was used to correct a mutant paternal MYBPC3 allele in human preimplantation embryos. 2....