Strict glucose control does not improve outcomes in acute ischemic stroke patients
1. In this randomized controlled trial, intensive hyperglycemia treatment did not lead to improved outcomes compared to standard treatment in...
Polygenic risk and lifestyle factors independently influence dementia risk
1. In this retrospective cohort study, patients with high polygenic risk scores and unhealthy lifestyle factors were more likely to...
Flexible ICU family visits not effective at reducing delirium incidence
1. In this randomized controlled trial, there was no difference in the incidence of delirium between flexible family visitation and...
Recombinant zoster vaccine reduced incidence of herpes zoster in autologous stem cell transplant recipients
1. In this randomized controlled trial, autologous hematopoietic stem cell transplantation patients who received 2 recombinant zoster vaccine doses had...
Recombinant zoster vaccine reduced incidence of herpes zoster in autologous stem cell transplant recipients
1. In this randomized controlled trial, autologous hematopoietic stem cell transplantation patients who received 2 recombinant zoster vaccine doses had...
Tanezumab provides modest benefit for osteoarthritis
1. In this randomized controlled trial, subcutaneous tanezumab resulted in moderate improvements in joint pain and physical function for patients...
Defining airflow obstruction as FEV1:FVC of less than 0.70 optimal compared to other fixed thresholds for COPD
1. In this retrospective cohort study, an FEV1:FVC threshold of 0.71 was the best fit for discriminating COPD-related events, though...
Alzheimer’s Disease imaging biomarkers slightly improve prediction of memory decline
1. In this prospective cohort, Alzheimer’s Disease biomarkers derived from imaging, namely amyloid, tau, and cortical thickness estimates, had a...
Post-procedure stroke rates stable in TAVR patients in United States
1. In this retrospective cohort study, the rate of 30-day post-procedure stroke after transcatheter aortic valve replacement (TAVR) remained stable...
Blood transfusions from female, previously pregnant, or sex-discordant donors do not increase mortality
1. In this large retrospective cohort, there were no increases in mortality from red blood cell transfusions from female, previously...
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