SGLT2 inhibitors reduce the risk of kidney disease in patients with and without diabetes
1. SGLT2 inhibitors reduced the risk of kidney disease progression by 37% overall, with comparable effects in patients with and...
Personalized cooler dialysate does not reduce cardiovascular events for hemodialysis patients
1. There was no significant difference in the risk of cardiovascular-related death or hospitalization between the personalized cooler dialysate group...
Heliobacter pylori eradication significantly reduces the risk of short-term hospitalization in patients taking low dose aspirin
1. In the first 2.5 years after H. pylori eradication, there was a 65% reduction in hospitalizations and deaths due...
United States-based chemotherapy regimen for Ewing sarcoma is more effective and safer than the standard European regimen
1. The United States regimen had greater event-free survival and less associated febrile neutropenia compared to the European regimen. 2....
Renal artery denervation is effective and well-tolerated for blood pressure reduction
1. Patients assigned to renal artery denervation had significantly lower office and ambulatory blood pressures at 36-month follow-up compared to...
Artificial intelligence algorithm may increase atrial fibrillation detection rate in ambulatory setting
1. The detection rates for newly diagnosed atrial fibrillation were almost five times greater between high-risk patients compared to low-risk...
Nivolumab plus ipilimumab improves recurrence-free survival in patients with resected advanced melanoma
1. 4-year recurrence-free survival was significantly higher with nivolumab plus ipilimumab compared to placebo. 2. Overall survival was significantly higher...
Stereotactic body radiation does not improve outcomes in patients with advanced Merkel cell carcinoma receiving nivolumab and ipilimumab
1. Objective response rate was not significantly different in patients treated with stereotactic body radiotherapy compared to those without. 2....
Linzagolix significantly reduces heavy menstrual bleeding in women with uterine fibroids
1. Linzagolix (100 mg and 200 mg) significantly reduced heavy menstrual bleeding in women with uterine fibroids compared to placebo....
Antihypertensives reduce the rate of progressive aortic root dilation in Marfan syndrome
1. Compared to control, ARBs reduced the annual rate of increase of the aortic root Z score by approximately one-half....
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