Dupilumab reduces exacerbations in COPD with type 2 inflammation
1. In this randomized controlled trial, patients with chronic obstructive pulmonary disease (COPD) and type 2 inflammation who received dupilumab...
Oral sebetralstat provides early symptom relief for hereditary angioedema attacks
1. In this randomized controlled trial, oral sebetralstat provided faster times to the beginning of symptom relief than placebo in...
APOE3 Christchurch heterozygosity may delay cognitive impairment in Alzheimer’s disease
1. Carriers of the E280A variant of presenilin 1 (PSEN1E280A) who were heterozygous for the apolipoprotein E3 Christchurch variant (APOE3Ch)...
Early asthma and COPD intervention decreases healthcare utilization
1. In this randomized controlled trial, adults with undiagnosed asthma or chronic obstructive pulmonary disease (COPD) who received pulmonologist-directed treatment...
Self-expanding valve has lower rates of dysfunction than balloon-expandable valve for small aortic annulus
1. In this randomized controlled trial, a self-expanding supra-annular valve was superior to a balloon-expandable valve for bioprosthetic-valve dysfunction among...
Aficamten improves oxygen uptake in patients with obstructive hypertrophic cardiomyopathy
1. In this randomized controlled trial, aficamten significantly improved peak oxygen uptake in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM)...
Nutrition source does not influence weight gain for moderate-to-late-preterm infants
1. In this randomized controlled trial, the body-fat percentage among preterm infants was similar between those who received parenteral nutrition...
Olezarsen effectively lowers triglycerides in patients with familial chylomicronemia syndrome
1. In this randomized controlled trial, 80 mg of olezarsen, but not 50 mg, significantly reduced triglyceride levels compared to...
Resistance training not superior to neuromuscular exercises for hip osteoarthritis
1. In this randomized controlled trial, progressive resistance training (PRT) was not superior to neuromuscular exercise (NEMEX) in improving functional...
Nirmatrelvir does not decrease symptom duration in COVID-19
1. In this randomized controlled trial, there was no difference in the median time to sustained alleviation of coronavirus disease...
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