Non-TNF-targeted therapies more effective than anti-TNF agents in uncontrolled rheumatoid arthritis
1. The addition of a non-TNF-targeted biologic therapy is superior to the addition of an anti-TNF biologic therapy in patients...
Team-based care systems compare favorably with traditional practice models
1. Compared with traditional practice models, patients receiving care as part of a team-based approach utilized care less frequently at...
Vasopessin not shown to improve kidney function or clinical outcomes in septic shock
1. There was no significant difference in 28-day mortality between those receiving vasopressin vs. norepinephrine. 2. There was no significant...
All glucose-lowering medications effective, but some offer lower hypoglycemia risks
1. There was no difference in cardiovascular or all-cause mortality between any of the various glucose-lowering agent combinations 2. Each...
Among sepsis survivors, primary care interventions not associated with improved mental health outcomes
1. Compared to standard care, 6 months of primary care interventions were not associated with any improvement in mental health-related...
Opioids for chronic non-cancer pain linked to increased mortality
1. Long-term opioid therapy for chronic non-cancer pain is associated with an increase in all-cause mortality. 2. Increased mortality was...
High sodium consumption associated with cardiovascular disease in patients with chronic kidney disease
1. This study quantified sodium intake by measuring the 24-hour urinary sodium excretion, and found that among patients with chronic...
Bariatric surgery associated with sustained improvements in mobility and joint pain
1. Bariatric surgery was associated with clinically significant improvements in bodily pain, physical function, joint pain, and joint function at...
Sepsis associated with susceptibility to further infections and immunosuppression
1. Patients with sepsis were predisposed to ICU-acquisition of further infections. 2. Sepsis is associated with a degree of immunosuppression....
Expiratory central airway collapse associated with poor quality of life
1. Expiratory central airway collapse is associated with chronic obstructive pulmonary disease and a poorer quality of life. 2. However,...
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