Tiotropium linked with improved outcomes in early-stage COPD
1. Patients with mild or moderate COPD (chronic obstructive pulmonary disease) randomized to receive tiotropium had a significantly higher FEV1...
Improvement in diet quality linked to decreased all-cause mortality
1. Dietary quality, scored against three well validated dietary rubrics, as well as all-cause mortality were tracked in a large...
Treatment of subclinical hypothyroidism ineffective in older adults
1. There were no significant differences at one year regarding hypothyroid-related symptoms or cardiovascular outcomes between patients with subclinical hypothyroidism...
Lithium during pregnancy linked to modest increase in cardiac malformations
1. There has been concern about the linkage between lithium use during pregnancy and a risk of cardiac malformations, specifically...
Dabigatran linked to fewer major bleeding events than warfarin in ablation: The RE-CIRCUIT trial
1. The incidence of major bleeding events up to 8 weeks after catheter-directed atrial fibrillation ablation was significantly lower in...
Significant decline in mortality related to diabetes from 1998 to 2014
1. In a large Swedish registry-cohort study, the authors report significant declines in all-cause mortality and diabetes-related complications in patients...
Extended rivaroxaban superior to aspirin in lowering risk of recurrent venous thromboembolism: The EINSTEIN CHOICE trial
1. The EINSTEIN CHOICE trial involved patients who had a history of venous thromboembolism (VTE) and had completed 6 to...
JAK 1 and 2 inhibitor superior to adalimumab in treatment of rheumatoid arthritis: The RA-BEAM trial
1. Baricitinib, an oral, once-daily inhibitor of JAK1 and JAK2, has shown promise in the treatment of rheumatoid arthritis (RA)....
No difference between therapeutic hypo- and normo-thermia with in-hospital cardiac arrest in children
1. In children who suffered in-hospital cardiac arrest, there was no significant difference in 1-year survival in those randomized to...
Radiolabeled somatostatin analogue linked with improved survival in neuroendocrine tumors
1. 177Lu-Dotatate, a radiolabeled somatostatin analogue, was associated with increased progression-free survival and decreased overall mortality compared to standard therapy...