Ecopipam reduces tics in children with Tourette syndrome
1. In a phase 2 trial of patients with Tourette syndrome, ecopipam, a selective dopamine receptor antagonist, was associated with a...
Perfluorohexyloctane drops significantly improve dry eye due to Meibomian gland dysfunction
1. In a phase 3 randomized controlled trial of about 600 patients with dry eye disease, NOV03, a perfluorohexyloctane eye...
Balanced intravenous solutions reduce risk of hyperchloremia in the pediatric intensive care unit
1. In a randomized controlled trial of critically ill pediatric patients requiring intravenous fluid therapy, children receiving saline were significantly...
Post-operative exclusive human milk diet improves growth in neonates with single ventricle physiology
1. In a small randomized controlled trial, the median velocity of weight gain was significantly higher at 30 days post-operatively in...
Meta-analysis shows significant decrease in age-related macular degeneration risk with metformin use
1. In a systematic review and meta-analysis of observational studies on patients with diabetes, metformin use was associated with a...
Double embryo transfer may be associated with neonatal risks
1. In a large Swedish cohort of singleton births following the use of assisted reproductive technology, double embryo transfer was...
Prevalence of keratoconus estimated at more than 3%
1. In a small cohort of young adults in Australia, the community prevalence of keratoconus was 3.4% based on corneal...
Maternal unintentional injury during pregnancy associated with higher risk of cerebral palsy
1. Based on a large cohort study, children born to mothers who had an unintentional injury during pregnancy had a...
Airway impedance may aid diagnosis of gastroesophageal reflux and aspiration in children
1. In a small prospective cohort of children undergoing direct laryngoscopy and endoscopy, airway impedance did not correlate with gastroesophageal reflux...
Preclinical detectable phase for open-angle glaucoma estimated at 10 years
1. Based on a large Swedish cohort screened for open-angle glaucoma, the estimated preclinical detectable phase for glaucoma was estimated...