Early weight-bearing after ankle surgery may be as effective and more cost-efficient than delayed weight-bearing
1. Patients in the early weight-bearing group showed better recovery than those in the delayed weight-bearing group at 4 months...
Sintilimab improves survival in advanced non-metastatic nasopharyngeal carcinoma
1. Patients in the sintilimab group reported a significantly greater event-free survival at 36 months compared to the standard therapy...
Vimseltinib may be promising in treating symptomatic tenosynovial giant cell tumour
1. Tumor response rate at 25 weeks was significantly greater in vimseltinib than placebo. 2. Most adverse events were mild-to-moderate...
Intravenous tenecteplase shows no benefit in minor ischaemic stroke with intracranial occlusion
1. Return to baseline function was comparable in tenecteplase and standard-of-care groups. 2. More deaths and intracranial hemorrhages were reported...
Image-guided assessment of coronary inflammation improves cardiac risk prediction for patients without obstructive coronary artery disease
1. Individuals with elevated fat attenuation index scores without obstructive coronary artery disease had significantly increased rates of major adverse...
Bimekizumab safe and effective for treatment of moderate-to-severe hidradenitis suppurative
1. Significantly more patients in the bimekizumab group than placebo reported improved clinical response at week 16. 2. Treatment-related adverse...
Bariatric surgery may improve rates for spontaneous ovulation in patients with polycystic ovarian syndrome and obesity
1. Women in the surgical group reported 2.5 times more spontaneous ovulations than in medical therapy. 2. Those assigned to...
Decompressive craniectomy may benefit patients with supratentorial intracerebral hemorrhage
1. Fewer patients in the decompressive craniectomy group had an mRS score of 5-6 compared to medical treatment alone, although...
Short-term androgen deprivation therapy does not improve survival in patients receiving postoperative radiotherapy for prostate cancer
1. There was no significant difference in metastasis-free survival between the ADT and non-ADT groups over 10 years. 2. Adverse...
Ticagrelor monotherapy reduces bleeding risk following percutaneous coronary intervention
1. Clinically relevant bleeding was significantly lower with ticagrelor monotherapy than in the ticagrelor plus aspirin group. 2. Major cardiovascular...