Viral vector based gene therapies show promise for treating focal epilepsy [PreClinical]
1. Seizures are often associated with accumulation of extracellular glutamate due to the synchronous discharges of excitatory neurons. 2. Treatment...
Radhika Agarwal is currently an MD/PhD student at Harvard Medical School. She completed her undergraduate degrees in Biochemistry and Biology at Indiana University Bloomington, where she was a Herman B Wells Scholar, the most competitive scholarship offered by the university. Her undergraduate research on the mechanisms of bacterial surface adhesion has been recognized with several awards, including a prestigious Goldwater Scholarship and the Indiana University Provost’s Award for Research Excellence. After graduation, Radhika enrolled in the Harvard-MIT Health Sciences and Technology program and joined the Harvard-MIT MD/PhD program. Her graduate work involves the application of CRISPR gene editing technologies to model mutations that cause heart disease in induced pluripotent stem cell derived cardiomyocytes. Radhika is interested in translating advances in genetic tools and research to patient care. Additionally, she is passionate about effective science communication, and serves as managing correspondent for Science in the News, a Harvard graduate student organization with a mission to bridge the communication gap between scientists and non-scientists.
1. Seizures are often associated with accumulation of extracellular glutamate due to the synchronous discharges of excitatory neurons. 2. Treatment...
1. BEACON CRC is a multicenter, randomized, phase 3 clinical trial evaluating the triplet combination of binimetinib (BINI, a MEK...
1. Intra-articular fractures (IAFs) often lead to posttraumatic osteoarthritis (PTOA) through mechanisms that involve mitochondria. 2. In a porcine model...
1. Following cervical spinal cord injury, rhesus monkeys were grafted with human neural progenitor cells. 2. Over the course of...
1. A novel method – Antibody Detection by Agglutination-PCR (ADAP) – was developed to diagnose HIV in oral fluid samples....
1. A device for islet transplantation for type 1 diabetes was designed and demonstrated to be safe and retrievable in...
1. Repeated gastrointestinal infections in mice, in this case Salmonella enterica Typhimurium (ST), caused intestinal tissue inflammation which escalated with...
1. The β-chain constant region of the T cell receptor (TCR) was targeted to specifically eliminate a population of malignant...
1. An enzyme involved in thyroid hormone activation was found to be elevated in patients with pulmonary fibrosis. 2. Following...
1. GHRH and GHRH receptor levels are decreased in diabetic rats and humans. 2. Administration of GHRH agonists to diabetic...
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