No difference between tenofovir and placebo in reducing perinatal transmission of hepatitis B
1. Hepatitis B e-antigen (HBe-Ag) positive mothers receiving tenofovir daily from 28-weeks gestation to 2 months postpartum did not show...
Balanced crystalloids decreases adverse kidney events compared to saline among critically ill patients: The SMART trial
1. Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury...
Nusinersen improves motor function in children with later-onset spinal muscular atrophy: The CHERISH trial
1. Intrathecal injections of nusinersen in pediatric later-onset spinal muscular atrophy (SMA) patients were associated with increased clinical motor function...
Acute lymphoblastic leukemia disease burden associated with safety and efficacy of CD19-CAR therapy
1. Patients with a higher disease burden of acute lymphoblastic leukemia (ALL) treated with CD19-specific chimeric antigen receptor (CAR) T...
Viral respiratory infections associated with increased risk of acute myocardial infarction
1. In a self-controlled case series, patients were observed to have increased incidence of hospital admissions for acute myocardial infarction...
Live-birth rates similar among ovulating women undergoing fresh- or frozen-embryo transfer
1. No differences were observed in live-birth rate, rates of implantation, clinical pregnancy, overall pregnancy loss, or ongoing pregnancy incidents...
Chimeric antigen receptor T-cell therapy elicits treatment response in patients with refractory B-cell lymphoma
1. Patients with refractory diffuse large B-cell or follicular lymphoma demonstrated high rates of remission when treated with anti-CD19 directed...
Meningococcal B vaccine induces protective antibody response in adolescents and young adults
1. Healthy adolescents and young adults treated with the Neisseria meningitidis vaccine MenB-FHbp had increased bactericidal antibody responses (hSBA titer)...
Recombinant viral vector treatment sustains endogenous factor IX activity in patients with hemophilia B
1. A one-time infusion of a recombinant viral vector with a highly expressed factor IX gene resulted in sustained endogenous...
Erenumab linked to decreased episodic migraine frequency: The STRIVE trial
1. Monthly injections of erenumab were associated with reduced migraine frequency, decreased use of acute migraine medication, and decreased migraine...