Preoxygenation with noninvasive ventilation reduces hypoxemia during intubation
1. In this randomized controlled trial involving critically ill adults undergoing tracheal intubation, those who were preoxygenated with bilevel-positive airway...
Genome sequencing may offer diagnostic utility beyond exome sequencing at acceptable cost
1. In this cohort study of families with suspected Mendelian disorders for whom preliminary genetic testing had not revealed a...
Zodasiran associated with reduced triglyceride levels among adults with mixed hyperlipidemia
1. In this randomized controlled trial, adults with mixed hyperlipidemia who received zodasiran had dose-dependent decreases in triglyceride levels compared...
Early blood-pressure control not associated with improved outcomes in patients with undifferentiated stroke
1. In this randomized controlled trial, patients with stroke symptoms who were given antihypertensives en route to the hospital did...
Transcatheter aortic valve implantation non-inferior to surgical replacement in low-to-intermediate risk patients
1. In this randomized controlled trial, it was found that those who received transcatheter aortic valve replacement (TAVI) did not...
Empagliflozin does not decrease risk of hospitalization or death after myocardial infarction
1. In this randomized controlled trial, empagliflozin was not shown to decrease the risk of hospitalization for heart failure or...
Albuminuria within high normal range associated with chronic kidney disease progression
1. In this prospective cohort study involving patients with chronic kidney disease (CKD), those with urine albumin levels on the...
Chest radiograph deep-learning model for cardiac event risk estimation
1. In this retrospective study, the chest X-ray cardiovascular disease (CXR CVD)-risk model performed similarly to the standard atherosclerotic (AS)...
Minimally invasive surgery provides functional benefit in acute supratentorial intracerebral hemorrhage
1. In this randomized controlled trial, patients who underwent minimally invasive surgical evacuation of a hematoma followed by medical management...
Elafibranor associated with biochemical response in patients with primary biliary cholangitis
1. In this randomized controlled trial, primary biliary cholangitis (PBC) patients who received elafibranor had significantly improved serum markers of...