Scrub typhus linked to high disease burden in rural India
1. In this cohort study, scrub typhus was a common cause of febrile illness in rural South India, with an...
Low-dose yellow fever vaccine non-inferior to standard dose
1. This randomized controlled trial conducted in Kenya and Uganda assessed whether fractional doses of the 17D-204 yellow fever vaccine...
CAR+ T-cell lymphoma linked to cilta-cel therapy in myeloma
1. This study describes two cases of malignant monoclonal T-cell lymphoproliferation following ciltacabtagene autoleucel (cilta-cel) Chimeric Antigen Receptor T-cell (CAR...
Abelacimab reduces bleeding risk compared to rivaroxaban in atrial fibrillation
1. In this randomized controlled trial, abelacimab led to significantly lower rates of major or clinically relevant nonmajor bleeding compared...
Vutrisiran reduces mortality in transthyretin amyloidosis with cardiomyopathy
1. Vutrisiran treatment reduced the risk of death and recurrent cardiovascular events compared to placebo in patients with transthyretin amyloidosis...
Ponsegromab improves boy weight in cancer-related cachexia
1. Ponsegromab significantly increased body weight in patients with cancer cachexia and elevated GDF-15 levels compared to placebo at 12...
Semaglutide reduces body weight and pain symptoms in obese patients with knee osteoarthritis
1. In this randomized controlled trial, once-weekly semaglutide led to significant weight loss compared to placebo over 68 weeks in...
Asciminib improves outcomes in chronic myeloid leukemia
1. In this randomized controlled trial, among adults diagnosed with chronic myeloid leukemia (CML), asciminib demonstrated a significantly higher major...