Grading carcinoembryonic antigen levels can enhance prognostic stratification in colorectal cancer
1. Higher CEA levels in patients with colorectal cancer are indicative of aggressive tumour phenotypes and survival Evidence Rating Level:...
Gastroenterology
Reports of high-impact gastroenterology studies by medical professionals
Glucagon-like peptide 1 receptor agonists may decrease rates of inflammatory bowel disease flares
1. The use of glucagon-like peptide 1 (GLP-1) agonists in patients with inflammatory bowel disease (IBD) was associated with few...
Glucagon-like peptide-1 receptor agonists may impact outcomes of endoscopy
1. The use of glucagon-like peptide 1 (GLP-1) receptor agonists in adults with type 2 diabetes mellitus (T2DM) was not...
High levels of serum hypersensitive C-reactive protein are associated with non-alcoholic fatty liver
1. Increased levels of hypersensitive C-reactive protein was associated with increased risk of non-alcoholic fatty liver disease among non-obese individuals. ...
Computer-aided detection may improve detection of polyps and adenomas compared with conventional colonoscopy
1. In this updated systematic review and meta-analysis, computer-aided detection found more polyps and adenomas per colonoscopy compared with standard...
Weekly insulin efsitora alfa is non-inferior to daily insulin degludec for reducing HbA1c in type 1 diabetes
1. Once weekly efsitora demonstrated non-inferiority compared with degludec with regards to change in HbA1c. 2. Patients in the efsitora...
Liver transplantation plus chemotherapy improves survival in patients with unresectable colorectal liver metastases
1. 5-year survival was significantly greater in the liver transplantation plus chemotherapy group compared to chemotherapy alone. 2. Serious adverse...
Tulisokibart effectively induces clinical remission in moderately to severely active ulcerative colitis
1. In this randomized controlled trial, among patients with moderately to severely active ulcerative colitis, tulisokibart, a monoclonal antibody directed...
Naldemedine may be effective for opioid-induced constipation in patients with cancer
1. In a randomized double-blind placebo-controlled study, naldemedine use was associated with constipation prevention and a significant improvement of constipation-related...
Sarcopenia is a risk factor for postoperative complications in adults with inflammatory bowel disease
1. Sarcopenia is associated with an increased risk of adverse postoperative outcomes in older adults with inflammatory bowel disease (IBD)....
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