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Sotorasib plus panitumumab may be a promising treatment option for colorectal cancer
1. While not statistically significant, the use of sotorasib plus panitumumab may have a 30% relative risk reduction in the...
Gastroenterology
Reports of high-impact gastroenterology studies by medical professionals
Genomic sequencing identifies variants linked to congenital diarrhea and enteropathies
1. In this cross-sectional study, nearly half of the infants with congenital diarrhea and enteropathies (CODEs) had identifiable causal variants,...
Cholecystectomy may be feasible in patients with silent common duct stones
1. In patients with symptomatic gallbladder stones who were found to have asymptomatic concomitant common bile duct stones (CBDS), laparoscopic...
Durvalumab and bevacizumab plus chemoembolization improves progression-free survival in hepatocellular carcinoma
1. Progression-free survival was significantly greater in the durvalumab plus bevacizumab group compared to placebo. 2. Common treatment-related adverse events...
Perioperative chemotherapy improves survival in esophageal cancer
1. Among patients with resectable esophageal cancer, perioperative chemotherapy with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) resulted in improved survival...
Plozasiran reduces triglyceride levels and acute pancreatitis incidence in persistent chylomicronemia
1. In this randomized controlled trial, among patients with persistent chylomicronemia, it was found that plozasiran more effectively reduced fasting...
Transarterial chemoembolization with pembrolizumab and levatinib improves survival in unresectable hepatocellular carcinoma
1. Progression-free survival was significantly greater in the lenvatinib plus pembrolizumab group compared to placebo. 2. Overall survival was higher...
High flow nasal cannula reduces hypoxia for obese patients undergoing endoscopy
1. The use of high flow nasal cannula (HFNC) in patients with obesity undergoing sedated gastrointestinal endoscopy significantly reduced the...
Endoscopic semi-blunt dissection technique safe and effective for gastric submucosal tumors
1. Use of the semi-blunt dissection technique with endoscopic resection of gastric submucosal tumours was associated with a smaller maximum...
Characterization of the increased incidence of alcohol-associated hepatitis noted in Ontario, Canada in past two decades
1. From 2002 to 2021, the incidence rate of alcohol-associated hepatitis in Ontario, Canada increased by 8% annually, with rates...