![Maternal cell-free DNA sequencing superior to standard aneuploidy screening [CARE Study]](https://www.2minutemedicine.com/wp-content/uploads/2014/02/47-karyotype-350x250.jpg)
Australian couple-based genetic screening program feasible and accepted
1. In this prospective cohort study, genetic screening among Australian reproductive couples was widely accepted and associated with low decisional...
Pharma
Tranexamic acid reduces life-threatening postpartum bleeding
1. Tranexamic acid significantly reduced life-threatening postpartum bleeding. 2. There were no differences in the risk of thromboembolic events. Evidence...
RAMOSE Phase II trial finds promising results for osimertinib and ramucirumab in non-small cell lung cancer
1. Treatment of patients with tyrosine kinase inhibitor (TKI)-naïve epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) with...
Novo Nordisk’s Rybelsus demonstrates reduction in cardiovascular events for patients with Type 2 diabetes and cardiovascular disease
Rybelsus in combination with standard T2DM therapy reduced the risk of major cardiovascular events by 14% in patients with diabetes...
Endometriosis and uterine fibroids associated with a greater risk of mortality due to gynecologic cancers
1. A history of endometriosis and uterine fibroids in women was associated with a greater risk of premature mortality and...
Intellia Therapeutics: NTLA-2002 CRISPR-based therapy reduces rates of Hereditary Angioedema (HAE) attacks
CRISPR gene editing based treatment reduced HAE attacks rates by up to 80%. NTLA-2002 was well tolerated by patients. The...
Iterum’s Sulopenem receives FDA approval for treatment of uncomplicated urinary tract infections
Sulopenem was superior to amoxicillin/clavulanate and ciprofloxacin in treating antimicrobial resistant uncomplicated urinary tract infections. The antibiotic was safe and...
Astellas: Vyloy improves survival in patients with advanced gastric cancer
Vyloy plus standard-of-care chemotherapy extended overall survival in patients with advanced gastric cancer. The rate of grade 3 or higher...
Clearside’s CLS-AX shows promise in treatment of wet age-related macular degeneration
Patients with wet age-related macular degeneration receiving CLS-AX achieved stable visual acuity, and retinal thickness for up to six months....
Sanofi’s Sarclisa approved as first-line for transplant-ineligible multiple myeloma patients
Sarclisa in combination with the VRd regiment was superior to VRd alone in improving survival in stem cell transplant ineligible...