• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan+
  • Wellness
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Career
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan+
  • Wellness
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Career
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Maternal obesity associated with increased risk of perinatal ischemic stroke

byPaary BalakumarandAlex Chan
February 26, 2025
in Chronic Disease, Emergency, Neurology, Obstetrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. There is a dose-response relationship between maternal body mass index (BMI) and perinatal ischemic stroke (PIS) risk

Evidence Rating Level: 2 (Good) 

This nationwide cohort study investigated the association between maternal early pregnancy body mass index (BMI) and the risk of perinatal ischemic stroke (PIS) in infants. Perinatal ischemic stroke, occurring from 20 weeks’ gestation to 28 days post-birth, affects approximately 1 in 3,000 term-born infants and is associated with significant neurodevelopmental consequences. Given the rising prevalence of maternal obesity and its link to obstetric complications, this study aimed to clarify whether maternal overweight and obesity increase the risk of PIS. The study included 2,140,852 singleton births in Sweden from 1998 to 2019, with 415 infants diagnosed with PIS. Maternal BMI was categorized per WHO criteria: normal weight (18.5–24.9), overweight (25–29.9), and obesity classes I (30–34.9), II (35–39.9), and III (≥40). Adjusted rate ratios (aRRs) for PIS were calculated using Poisson log-linear regression. There was a dose-response relationship between maternal BMI and PIS risk. Compared to infants of normal-weight mothers (19/100,000 births), PIS rates rose to 22/100,000 for overweight mothers, 35/100,000 for obesity class II, and 40/100,000 for class III. The aRRs for PIS were 1.16 (95% CI 0.91–1.46) for overweight, 1.82 (95% CI 1.34–2.44) for obesity class I, and 1.96 (95% CI 1.27–2.91) for obesity classes II-III. These findings suggest maternal obesity is an independent risk factor for PIS, increasing risk nearly twofold in severe obesity. The study demonstrates the importance of maternal weight management and highlights the need for targeted prenatal care strategies to mitigate PIS risk. Further research should explore underlying mechanisms, including placental dysfunction and inflammation.

Click to read the study in Neurology

Image: PD

©2025 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc. 

RELATED REPORTS

#VisualAbstract: Tirzepatide Superior to Semaglutide in Obese Adults Without Diabetes

Chronic fatigue is a common symptom associated with transient ischemic attack

2 Minute Medicine Rewind May 19th, 2025

Tags: emergency medicineneurologyobesityobstetricsstroke
Previous Post

#VisualAbstract: Addition of Aerobic Physical Activity to Resistance Exercise Does Not Improve Pain or Function in Hip Osteoarthritis

Next Post

Home-based dynamic intermittent pneumatic compression therapy improves chronic stroke outcomes

RelatedReports

#VisualAbstract: Tirzepatide Superior to Semaglutide in Obese Adults Without Diabetes
StudyGraphics

#VisualAbstract: Tirzepatide Superior to Semaglutide in Obese Adults Without Diabetes

May 20, 2025
Chronic Disease

Chronic fatigue is a common symptom associated with transient ischemic attack

May 19, 2025
Weekly Rewinds

2 Minute Medicine Rewind May 19th, 2025

May 19, 2025
Food environment associated with gestational diabetes
Pharma

Eli Lilly Takes Legal Action Against Telehealth Startups

May 15, 2025
Next Post
Quick Take: Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial

Home-based dynamic intermittent pneumatic compression therapy improves chronic stroke outcomes

Prevalence of hypertension among adolescents varies by race and BMI

Patients with coronary artery disease have sustained elevation in blood pressure following exercise

Variability in interpretation of breast biopsy slides associated with low verification of atypia and ductal carcinoma in situ

2 Minute Medicine Rewind March 3, 2025

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Reduced-dose apixaban noninferior to full dose for cancer-associated thrombosis
  • #VisualAbstract: Tirzepatide Superior to Semaglutide in Obese Adults Without Diabetes
  • Single-dose baloxavir linked to reduced influenza transmission
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Career
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.