#VisualAbstract: Immunotherapy-Based Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
1. The complete response rates (pathological and clinical) were similar (~55%) in both groups. 2. Grade 3-4 adverse events rates ...
Tag: rectal cancer
Immunotherapy-Based Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
1. The complete response rates (pathological and clinical) were similar (~55%) in both groups. 2. Grade 3-4 adverse events rates ...
#VisualAbstract: Preoperative Treatment of Locally Advanced Rectal Cancer
Click to read this study in NEJM. ©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without ...
Neoadjuvant FOLFOX compared to Chemoradiotherapy in Locally Advanced Rectal Cancer
1. Patients who were randomized to neoadjuvant FOLFOX vs standard chemoradiation had similar disease-free and overall survival rates. 2. There ...
Neoadjuvant dostarlimab is a promising treatment option in locally advanced dMMR rectal cancer
1. All neoadjuvant dostarlimab patients had a clinical complete response and no patients needed any additional treatments at the study ...
Adherence to pre-treatment imaging guidelines for staging in rectal cancer is increasing, but a gap still remains
1. Adherence to the guidelines increased from 38% to 56% between Fall 2016 and 2019; and from 37% to 70% ...
Capecitabine + oxaliplatin chemoradiotherapy does not increase survival, but increases toxicity, compared to capecitabine alone in the postoperative treatment of rectal cancer
1. A randomized controlled trial of patients with stage II and III rectal cancer found that adding oxaliplatin to the ...
Neoadjuvant pembrolizumab with chemoradiotherapy not supported for locally advanced rectal cancer after chemotherapy treatment
1. Although combining pembrolizumab to chemoradiotherapy as part of total neoadjuvant therapy after FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin) treatment was ...
#VisualAbstract: Pembrolizumab linked to longer cancer-free period in advanced MSI-H-dMMR colorectal cancer
1. In a phase 3 trial across 23 countries, Pembrolizumab displayed a longer cancer-free period when compared to the first ...
#VisualAbstract: Oxaliplatin-Based Adjuvant Chemotherapy for Rectal Cancer After Preoperative Chemoradiotherapy (ADORE)
1. Adjuvant FOLFOX improves disease-free survival in patients with pathologic Stage II or III rectal cancer after upfront surgery and preoperative ...