No advantage of continuous vs intermittent meropenem in critically ill patients – the MERCY trial
1. The MERCY trial revealed that continuous infusion of meropenem does not confer a significant advantage over intermittent administration in ...
Tag: septic shock
Addition of fludrocortisone to hydrocortisone is beneficial in management of septic shock
1. Patients treated for septic shock with fludrocortisone and hydrocortisone were less likely to die or be discharged to hospice ...
#VisualAbstract: Intravenous vitamin C increases mortality and organ dysfunction in sepsis patients
1. In patients with sepsis receiving a vasopressor in the intensive care unit (ICU), intravenous vitamin C was associated with ...
Intravenous fluid restriction does not improve septic shock outcomes
1. There was no significant difference in mortality among septic shock patients in the intensive care unit (ICU) between standard ...
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The SEPSISPAM trial: Mean arterial pressure targets in septic shock [Classics Series]
This study summary is an excerpt from the book 2 Minute Medicine's The Classics in Medicine: Summaries of the Landmark ...
High pediatric sequential organ failure assessment (pSOFA) score may predict hospital mortality in emergency department setting
1. In a large cohort study, children presenting to emergency departments with a score of 2 or higher on the ...
Pediatric emergency simulation training strengthens team performance and learner confidence, may improve outcomes
1. In this systematic review of studies on team-oriented simulation training for the care of the critically ill child, simulation improved ...
#VisualAbstract: Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
1. In this randomized clinical trial, intravenous infusion of high-dose vitamin C vs placebo for 96 hours resulted in no ...
Vitamin C may not provide benefit in sepsis with acute respiratory failure
1. In this randomized clinical trial, intravenous infusion of high-dose vitamin C vs placebo for 96 hours resulted in no ...
Adjunctive glucocorticoid therapy does not lower mortality in septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone ...